Data-Driven Assessment of Adolescents’ Mental Health During the COVID-19 Pandemic - 27/07/23
, Maytal Bivas-Benita, PhD a, Pinchas Akiva, PhD a, Nir Kalkstein, BSc a, Yoav Yehezkelli, MD, MHA a, b, Miri Mizrahi-Reuveni, MD b, Anat Ekka-Zohar, PhD b, Shirley Shapiro Ben David, MD b, Uri Lerner, PhD b, Gilad Bodenheimer, MD b, Shira Greenfeld, MD b
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Abstract |
Objective |
Adolescents’ mental health was severely compromised during the COVID-19 pandemic. Longitudinal real-world studies on changes in the mental health of adolescents during the later phase of the pandemic are limited. We aimed to quantify the effect of COVID-19 pandemic on adolescents’ mental health outcomes based on electronic health records.
Method |
This was a retrospective cohort study using the computerized database of a 2.5 million members, state-mandated health organization in Israel. Rates of mental health diagnoses and psychiatric drug dispensations were measured among adolescents 12 to 17 years of age with and without pre-existing mental history, for the years 2017 to 2021. Relative risks were computed between the years, and interrupted time series (ITS) analyses evaluated changes in monthly incidence rates of psychiatric outcomes.
Results |
The average population size was 218,146 in 2021. During the COVID-19 period, a 36% increase was observed in the incidence of depression (95% CI = 25-47), 31% in anxiety (95% CI = 23-39), 20% in stress (95% CI = 13-27), 50% in eating disorders (95% CI = 35-67), 25% in antidepressant use (95% CI = 25-33), and 28% in antipsychotic use (95% CI = 18-40). A decreased rate of 26% (95% CI = 0.80-0.88) was observed in ADHD diagnoses. The increase of the examined outcomes was most prominent among youth without psychiatric history, female youth, general secular Jewish population, youth with medium−high socioeconomic status, and those 14 to 15 years of age. ITS analysis confirmed a significantly higher growth in the incidence of psychiatric outcomes during the COVID-19 period, compared to those in previous years.
Conclusion |
This real-world study highlights the deterioration of adolescents’ mental health during the COVID-19 pandemic and suggests that youth mental health should be considered during health policy decision making.
Diversity & Inclusion Statement |
We worked to ensure sex and gender balance in the recruitment of human participants. We worked to ensure race, ethnic, and/or other types of diversity in the recruitment of human participants. We actively worked to promote sex and gender balance in our author group. The author list of this paper includes contributors from the location and/or community where the research was conducted who participated in the data collection, design, analysis, and/or interpretation of the work.
Le texte complet de cet article est disponible en PDF.Key words : mental health, COVID-19, cohort study
Plan
| The authors have reported no funding for this work. |
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| The research was performed with permission from Maccabi Health Services’ Institutional Review Board (MH6-0006-21). |
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| This work has been previously posted on a preprint server: 2022.01.06.22268809v2. |
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| Inbal Goldshtein, PhD, of the KI Institute, served as the statistical expert for this research. |
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| Author Contributions Conceptualization: Bilu, Flaks-Manov, Kalkstein, Yehezkelli, Greenfeld Data curation: Bilu Formal analysis: Bilu Investigation: Bilu, Bodenheimer Methodology: Bilu, Flaks-Manov Project administration: Akiva, Greenfeld Supervision: Bivas-Benita, Yehezkelli, Mizrahi-Reuveni, Ekka-Zohar, Shapiro Ben David, Lerner, Bodenheimer, Greenfeld Writing – original draft: Flaks-Manov, Bivas-Benita Writing – review and editing: Bilu, Akiva, Shapiro Ben David, Lerner, Bodenheimer, Greenfeld |
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| Disclosure: Drs. Bilu, Flaks-Manov, Bivas-Benita, Akiva, Yehezkelli, Mizrahi-Reuveni, Ekka-Zohar, Shapiro Ben David, Lerner, Bodenheimer, and Greenfeld and Mr. Kalkstein have reported no biomedical financial interests or potential conflicts of interest. |
Vol 62 - N° 8
P. 920-937 - août 2023 Retour au numéro
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