Three-dimensional Computed Tomography Scan of the Pelvic Bone in Isolated Epispadias: Analysis Before Surgical Correction - 10/10/23

Doi : 10.1016/j.urology.2023.05.050

Hooman Kamran ^a,^b, Masoud Bitaraf ^a, Roozbeh Tanhaeivash ^c, Abdol-Mohammad Kajbafzadeh ^a,^⁎,^{^{1
ORCID ID: 0000-0002-1973-3509}}
^a Pediatric Urology and Regenerative Medicine Research Center, Gene, Cell and Tissue Research Institute, Children’s Medical Center, Tehran University of Medical Sciences, Tehran, Iran
^b Student Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran
^c Katholisches Krankenhaus St. Johann Nepomuk, Erfurt, Germany

^⁎Address correspondence to: Abdol-Mohammad Kajbafzadeh, M.D., Pediatric Urology and Regenerative Medicine Research Center, Children's Medical Center, Tehran University of Medical Sciences, No. 62, Dr. Gharib's St, Keshavarz Boulevard, P.O. Box: 1419733151, Tehran, Iran.Pediatric Urology and Regenerative Medicine Research Center, Children's Medical Center, Tehran University of Medical SciencesNo. 62, Dr. Gharib's St, Keshavarz Boulevard, P.O. Box: 1419733151TehranIran

Résumé

Objective

To determine intrapelvic angles and distances in pure epispadias patients and compare them to normal values.

Methods

Using three-dimensional computed tomography, 17 intrapelvic dimensions (8 angles and 9 distances) were measured in 26 patients with pure epispadias (21 boys and 5 girls). These values were compared to normal values obtained from 6 patients (5 boys and 1 girl) who underwent either pelvic or abdominopelvic computed tomography for purposes unrelated to their bony pelvis.

Results

Significant differences were observed in five angles (sacroiliac joint angle, S1 tilt angle, sacral curvature, superior-inferior rotation of the pelvis, and pubococcygeal angle; P-value=.016, .044, .011, .020, and .001, respectively); these show less sacral rotation toward the axial plane, more sacral curvature, inferior rotation of the pelvis, and sacroiliac joints’ rotation toward the coronal plane in epispadias compared to controls. Also, two distances (pubic diastasis and anterior segment length of the pelvis; P-value=.002 and .012, respectively) had significant differences, showing wider pubic diastasis and shorter anterior segment in epispadias. However, the differences between other intrapelvic angles and distances were not statistically significant between the two groups.

Conclusion

In addition to the explanations hypothesized for the embryology of the exstrophy-epispadias complex, there can be other etiologies for both epispadias and bladder exstrophy to explain the differences between bony anatomies of the pelvis in these patients.

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