Differences caused by blood and secretion samples for the detection of Klebsiella pneumoniae using metagenomic next-generation sequencing: A comparative analysis - 13/10/23
Doi : 10.1016/j.jinf.2023.08.011
Weiming Yao 1, Shiyan Feng 1, Liuqing Yang, Yuanlong Lin
Department of Infectious Diseases, National Clinical Research Center for Infectious Disease, Shenzhen Third People's Hospital, The Second Affiliated Hospital, School of Medicine, Southern University of Science and Technology, Shenzhen, Guangdong, China
Mingxia Zhang, Kanru Cai
Institute for Hepatology, National Clinical Research Center for Infectious Disease, Shenzhen Third People's Hospital, The Second Affiliated Hospital, School of Medicine, Southern University of Science and Technology, Shenzhen, Guangdong, China
Hongzhou Lu ⁎ 
, Fuxiang Wang ⁎
, Fuxiang Wang ⁎ Department of Infectious Diseases, National Clinical Research Center for Infectious Disease, Shenzhen Third People's Hospital, The Second Affiliated Hospital, School of Medicine, Sou thern University of Science and Technology, Shenzhen, Guangdong, China
∗Correspondence to: Department of Infectious Diseases, National Clinical Research Center for Infectious Disease, Shenzhen Third People's Hospital, The Second Affiliated Hospital, School of Medicine, Southern University of Science and Technology, 29 Bulan Road, Longgang District, Shenzhen 518083, Guangdong, China.Department of Infectious Diseases, National Clinical Research Center for Infectious Disease, Shenzhen Third People's Hospital, The Second Affiliated Hospital, School of Medicine, Southern University of Science and Technology29 Bulan Road, Longgang DistrictShenzhenGuangdong518083China
Highlights |
• | Blood sampling is an efficient method for utilizing mNGS to detect pathogens such as Klebsiella pneumoniae. |
• | The quantity of Klebsiella pneumoniae reads identified in blood accounted for a small fraction of those in secretions. |
• | The number of microorganisms identified in blood was significantly fewer than those in secretions. |
• | The microorganisms detected in both blood and secretions constituted the largest fraction among those in blood. |
Plan
© 2023
The British Infection Association. Publié par Elsevier Masson SAS. Tous droits réservés.
Vol 87 - N° 5
P. 438-444 - novembre 2023 Retour au numéro
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