Dynamic Contrast Enhanced MR Perfusion and Diffusion-Weighted Imaging of Marrow-Replacing Disorders of the Spine : A Comprehensive Review - 23/01/24

Doi : 10.1016/j.rcl.2023.09.004

Onur Yildirim, MD ^a,^⁎ , Kyung K. Peck, PhD ^b, Atin Saha, MD, MS ^a, Sasan Karimi, MD ^a, Eric Lis, MD ^a
^a Department of Radiology, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA
^b Department of Medical Physics

^∗Corresponding author.

Résumé

Significant advancements in cancer treatment have led to improved survival rates for patients, particularly in the context of spinal metastases. However, early detection and monitoring of treatment response remain crucial for optimizing patient outcomes. Although conventional imaging methods such as bone scan, PET, MR imaging, and computed tomography are commonly used for diagnosing and monitoring treatment, they present challenges in differential diagnoses and treatment response monitoring. This review article provides a comprehensive overview of the principles, applications, and practical uses of dynamic contrast-enhanced MR imaging and diffusion-weighted imaging in the assessment and monitoring of marrow-replacing disorders of the spine.

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Keywords : Dynamic contrast-enhanced MR imaging, Diffusion-weighted imaging, Spinal metastases, Hypervascular metastases, Hypovascular metastases, Benign and malignant vertebral compression fractures, Atypical hemangiomas (intraosseous venous malformations), Chordoma