How should a cluster randomized trial be analyzed? - 11/02/24
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Abstract |
In cluster randomized trials, individuals from the same cluster tend to have more similar outcomes than individuals from different clusters. This correlation must be taken into account in the analysis of every cluster trial to avoid incorrect inferences. In this paper, we describe the principles guiding the analysis of cluster trials including how to correctly account for intra-cluster correlations as well as how to analyze more advanced designs such as stepped-wedge and cluster cross-over trials. We then describe how to handle specific issues such as small sample sizes and missing data.
Le texte complet de cet article est disponible en PDF.Keywords : Cluster randomized trials, Stepped-wedge trials, Cluster crossover trials, Analysis
Plan
Vol 72 - N° 1
Article 202196- février 2024 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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