Single-use negative pressure wound therapy versus conventional dressings for the reduction of surgical site infections in closed surgical incisions: Systematic literature review and meta-analysis - 22/02/24
, Amy Glasswell b , Ben Costa b, ⁎ Abstract |
Background |
To evaluate whether a single-use negative pressure wound therapy (sNPWT) device can reduce the incidence of surgical site infection (SSI) in at-risk patients with closed surgical incisions across a range of surgical specialties, compared with standard care.
Methods |
PubMed, Embase, Cochrane Library and ClinicalTrials.gov were searched from the period January 2011 to April 2021.
Results |
Out of 15,283 articles identified, 19 were included. A statistically significant improvement (p < 0.05) in the composite SSI (odds ratio [OR]: 0.36; 95 % confidence interval [CI]: 0.27–0.49), superficial SSI (OR: 0.30; 95 % CI: 0.17–0.53), and deep SSI (OR: 0.67; 95 % CI: 0.46–0.96) outcomes was observed with the sNPWT device compared with standard care in a pooled analysis of all surgical specialties.
Conclusion |
A −80 mmHg sNPWT device reduces the incidence of composite, superficial, and deep SSIs when compared with standard care across a heterogenous at-risk surgical population containing a variety of surgical specialties.
Le texte complet de cet article est disponible en PDF.Graphical abstract |
Highlights |
• | Surgical site infection is a clinically important complication with high morbidity. |
• | -80 mmHg sNPWT significantly reduces the incidence of deep SSI. |
• | -80 mmHg sNPWT significantly reduces SSI in Class I and Class II surgeries. |
• | -80 mmHg sNPWT is effective at reducing SSI in a range of surgical specialties. |
• | No significant difference was observed with sNPWT and SoC for organ-space SSI. |
Keywords : Surgical site infection, Surgical site complication, General surgery, Single-use negative pressure wound therapy, Systematic literature review, Meta-analysis
Plan
Vol 228
P. 70-77 - février 2024 Retour au numéro
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