Functional gallbladder disorder: Interim analysis of a prospective cohort study - 26/02/24
Abstract |
Background |
Functional gallbladder disorder (FGBD) remains a controversial indication for cholecystectomy.
Methods |
A prospective cohort study enrolled patients strictly meeting Rome criteria for FGBD, and cholecystectomy was performed. They were assessed pre- and 3 and 6 months postoperatively with surveys of abdominal pain and quality of life (RAPID and SF-12 surveys, respectively). Interim analysis was performed.
Results |
Although neither ejection fraction nor pain reproduction predicted success after cholecystectomy, the vast majority of enrolled patients had a successful outcome after undergoing cholecystectomy for FGBD: of a planned 100 patients, 46 were enrolled. Of 31 evaluable patients, 26 (83.9 %) reported RAPID improvement and 28 (93.3 %) SF12 improvement at 3- or 6-month follow-up.
Conclusion |
FGBD, strictly diagnosed, should perhaps no longer be a controversial indication for cholecystectomy, since its success rate for biliary pain in this study was similar to that for symptomatic cholelithiasis. Larger-scale studies or randomized trials may confirm these findings.
Le texte complet de cet article est disponible en PDF.Graphical abstract |
Highlights |
• | Cholecystectomy for functional gallbladder disorder (FGBD) remains controversial. |
• | Nearly all studies are low quality: retrospective, without clear inclusion criteria. |
• | We prospectively enrolled patients strictly meeting Rome criteria for FGBD. |
• | The high rate of success here was similar to that for noncontroversial indications. |
• | FGBD should no longer be a controversial indication for cholecystectomy. |
Keywords : Functional gallbladder disorder, Biliary dyskinesia, Gallbladder dysfunction, Cholecystectomy, ROME criteria
Plan
| ☆ | Prepared for American Journal of Surgery as an Original Article. |
Vol 229
P. 129-132 - mars 2024 Retour au numéro
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