Differences Between Keratometry and Total Keratometry Measurements in a Large Dataset Obtained With a Modern Swept Source Optical Coherence Tomography Biometer - 28/03/24

Doi : 10.1016/j.ajo.2023.12.003

Jascha A. Wendelstein ^1,^2,^3,^4,^⁎ , Peter C. Hoffmann ⁵, Kenneth J. Hoffer ^6,⁷, Achim Langenbucher ⁴, Oliver Findl ⁸, Manuel Ruiss ⁸, Matthias Bolz ^2,³, Kamran M. Riaz ⁹, Seth M. Pantanelli ¹⁰, Guillaume Debellemanière ¹¹, Damien Gatinel ¹¹, David L. Cooke ^12,¹³, Alice Galzignato ¹⁴, Tun Kuan Yeo ¹⁵, Theo G. Seiler ^1,^16,¹⁷, Martin Zinkernagel ¹⁶, Giacomo Savini ¹⁸
¹ From the Institut für Refraktive und Ophthalmo-Chirurgie (IROC) (J.A.W., T.G.S.), Zurich, Switzerland
² Department for Ophthalmology and Optometry (J.A.W., M.B.), Kepler University Hospital GmbH, Linz, Austria
³ Johannes Kepler University Linz (J.A.W., M.B.), Linz, Austria
⁴ Institute of Experimental Ophthalmology (J.A.W., A.L.), Saarland University, Homburg, Germany
⁵ Augen-und Laserklinik (P.C.H.), Castrop-Rauxel, Germany
⁶ Stein Eye Institute (K.J.H.), University of California, Los Angeles, California, CA, USA
⁷ St. Mary's Eye Center (K.J.H.), Santa Monica, California, CA, USA
⁸ Department of Ophthalmology (O.F., M.R.), Hanusch Hospital, Vienna Institute for Research in Ocular Surgery (VIROS), Vienna, Austria
⁹ Dean A. McGee Eye Institute, University of Oklahoma (K.M.R.), Oklahoma City, OK, USA
¹⁰ Department of Ophthalmology (S.M.P.), Penn State College of Medicine, Hershey, PA, USA
¹¹ Rothschild Foundation Hospital (G.D., D.G.), Department of Ophthalmology, Paris, France
¹² Great Lakes Eye Care (D.L.C.), Saint Joseph, MI, USA
¹³ Department of Neurology and Ophthalmology (D.L.C.), Michigan State University, College of Osteopathic Medicine, East Lansing, MI, USA
¹⁴ Studio Oculistico d'Azeglio (A.G.), Bologna, Italy
¹⁵ Tan Tock Seng Hospital (T.K.Y.), Department of Ophthalmology, Singapore, Singapore
¹⁶ Inselspital Bern (T.G.S., M.Z.), Universitätsklinik für Augenheilkunde, Bern, Switzerland
¹⁷ Klinik für Augenheilkunde (T.G.S.), Universitätsklinikum Düsseldorf, Duesseldorf, Germany
¹⁸ IRCCS – Fondazione Bietti (G.S.), Rome, Italy

^⁎Inquiries to Jascha Wendelstein, IROC – Institut für Refraktive- und Ophthalmo-Chirurgie Zürich, Stockerstrasse 37, CH-8002 Zürich, Switzerland; Department for Ophthalmology and Optometry, Kepler University Hospital GmbH, Krankenhausstrasse 9, 4020 Linz, Austria; Medical Faculty, Johannes Kepler University Linz, Altenberger Strasse 69, 4040 Linz, Austria; Tel.: +43 (0)5 7680 83 – 1048, Fax: +43 (0)5 7680 83 – 1822IROC – Institut für Refraktive- und Ophthalmo-Chirurgie Zürich, Stockerstrasse 37, CH-8002 Zürich, Switzerland; Department for Ophthalmology and Optometry, Kepler University Hospital GmbH, Krankenhausstrasse 9, 4020 Linz, AustriaMedical FacultyJohannes Kepler University LinzAltenberger Strasse 69Linz4040Austria

Résumé

Purpose

This study aimed to explore the concept of total keratometry (TK) by analyzing extensive international datasets representing diverse ethnic backgrounds. The primary objective was to quantify the disparities between traditional keratometry (K) and TK values in normal eyes and assess their impact on intraocular lens (IOL) power calculations using various formulas.

Design

Retrospective multicenter intra-instrument reliability analysis.

Methods

The study involved the analysis of biometry data collected from ten international centers across Europe, the United States, and Asia. Corneal power was expressed as equivalent power and astigmatic vector components for both K and TK values. The study assessed the influence of these differences on IOL power calculations using different formulas. The results were analyzed and plotted using Bland–Altman and double angle plots.

Results

The study encompassed a total of 116,982 measurements from 57,862 right eyes and 59,120 left eyes. The analysis revealed a high level of agreement between K and TK values, with 93.98% of eyes exhibiting an absolute difference of 0.25 D or less. Astigmatism vector differences exceeding 0.25 D and 0.50 D were observed in 39.43% and 1.08% of eyes, respectively.

Conclusions

This large-scale study underscores the similarity between mean K and TK values in healthy eyes, with rare clinical implications for IOL power calculation. Noteworthy differences were observed in astigmatism values between K and TK. Future investigations should delve into the practicality of TK values for astigmatism correction and their implications for surgical outcomes.

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Plan

Introduction

Patients and Methods

Study design

Exclusion of questionable measurement quality

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P. 102-114 - avril 2024 Retour au numéro

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Differences Between Keratometry and Total Keratometry Measurements in a Large Dataset Obtained With a Modern Swept Source Optical Coherence Tomography Biometer - 28/03/24

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