Factors associated with extent of COVID-19 outbreaks: A prospective study in a large hospital network - 09/05/24
, Catherine Monteil, MS, Valérie Souyri, MSN, Sandra Fournier, MDon behalf of the AP-HP Infection prevention and control teams1
Bienvenue sur EM-consulte, la référence des professionnels de santé.
Article gratuit.
Connectez-vous pour en bénéficier!
Résumé |
Background |
The COVID-19 pandemic has generated numerous hospital outbreaks. This study aimed to identify factors related to the extent of nosocomial COVID-19 outbreaks in the largest French public health institution.
Methods |
An observational study was conducted from July 2020 to September 2021. Outbreaks were defined as at least 2 cases, patients and/or health care workers (HCWs), linked by time and geographic location. Logistic regression was performed to identify risk factors for large outbreaks among nine variables: variant, medical ward, COVID-19 vaccination rate and incidence among HCWs and Paris population, number of weekly COVID-19 tests among HCWs and the positivity rate, epidemic waves.
Results |
Within 14 months, 799 outbreaks were identified: 450 small ones (≤6 cases) and 349 large ones (≥7 cases), involving 3,260 patients and 3,850 HCWs.
In univariate analysis, large outbreaks were positively correlated to geriatrics wards, COVID-19 incidence, and rate of weekly positive tests among HCWs; and negatively correlated to intensive care units, variant Delta, fourth wave, vaccination rates of the Paris region’s population and that of the HCWs.
In multivariate analysis, factors that remained significant were the type of medical ward and the vaccination rate among HCWs.
Conclusions |
Intensive care unit and high vaccination rates among HCWs were associated with a lower risk of large COVID-19 outbreaks, as opposed to geriatric wards, which are associated with a higher risk.
Le texte complet de cet article est disponible en PDF.Highlights |
• | The COVID-19 pandemic has generated numerous hospital outbreaks. |
• | Geriatric wards are more likely to develop large COVID-19 outbreaks. |
• | Large clusters are negatively correlated to intensive care units. |
• | A high vaccination rate among HCWs limits the size of hospital COVID-19 outbreaks. |
Key Words : Health care-associated infection, Infection control, SARS-CoV-2
Plan
| Conflicts of interest: None to report. |
Vol 52 - N° 6
P. 696-700 - juin 2024 Retour au numéro
Article précédent
- Incidence and risk factors of COVID-19 in a tertiary hospital and the effectiveness of booster vaccination among health care workers: A retrospective cohort study, January 2020 to June 2022
- Hae Ry Lee, Sung Ran Kim, Min Hee Cho, Da Eun Kim, Su Yeon Jang, Jae Eun Lee, Hye Rin Jeong, Hyeon Jeong Kang, Joon Young Song, Byung Chul Chun
- Nursing home wastewater surveillance for early warning of SARS-CoV-2-positive occupants—Insights from a pilot project at 8 facilities
- Shantini D. Gamage, Chetan Jinadatha, Vincent Rizzo, Jr., Piyali Chatterjee, Hosoon Choi, Lynn Mayo, Emma Brackens, Munok Hwang, Jing Xu, Morgan Bennett, Oleh Kowalskyj, Edward A. Litvin, Lisa Minor, Jody McClarin, Richard Hofman, Douglas Dulaney, Gary A. Roselle
Bienvenue sur EM-consulte, la référence des professionnels de santé.