Bathing with wipes impregnated with chlorhexidine gluconate to prevent central line-associated bloodstream infection in critically ill patients: A systematic review with meta-analysis - 09/05/24
, Vanessa de Brito Poveda, DNS b , Juliana Rizzo Gnatta, DSc b , Ramon Antonio Oliveira, DSc b, ⁎ Résumé |
Background |
Recommendations for different types of bathing to prevent central line-associated bloodstream infections (CLABSI) are still divergent. The objective of this study was to verify whether bed bathing with wipes impregnated with 2% chlorhexidine (CHG) compared to conventional bed bathing is more effective in preventing CLABSI.
Methods |
Systematic review of the literature by consulting the electronic databases PubMed/Medline, Embase, CINAHL, Scopus, and Web of Science from the date of inception until July 1, 2023, with no language or time restrictions.
Results |
A total of 84,462 studies were examined, of which 6 were included in the meta-analysis. Data from 20,188 critical care patients included in primary studies were analyzed. The meta-analysis found that bed bathing with wipes impregnated with 2% CHG reduced the risk of CLABSI by 48% compared to conventional bed bathing (risk ratio 0.52; 95% confidence interval, 0.37-0.73), and this is moderate-quality evidence. The reduction in length of stay in the intensive care unit and length of hospital stay as well as the risk of death were not significantly different between the study groups. Whether bed bathing with 2% CHG-impregnated wipes increases the occurrence of skin reactions is unclear.
Conclusions |
This meta-analysis provides moderate-quality evidence that daily bathing with 2% CHG-impregnated wipes is safe and helps prevent CLABSI among adult intensive care unit patients.
Le texte complet de cet article est disponible en PDF.Highlights |
• | CHG-impregnated wipes reduce CLABSI risk by 48%. |
• | Moderate-quality evidence supports daily CHG bathing. |
• | No significant impact on skin allergies. |
Key Words : Critical care, Central venous catheters, Infection control
Plan
| Conflicts of interest: None to report. |
Vol 52 - N° 6
P. 731-738 - juin 2024 Retour au numéro
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