Traumatic lower extremity amputation as a risk factor for venous thromboembolism - 11/05/24
, Emanuele Lagazzi , Jefferson A. Proaño-Zamudio , Wardah Rafaqat, May Abiad, Michael DeWane , Charudutt N. Paranjape , Haytham M.A. Kaafarani , George C. Velmahos, John O. Hwabejire ⁎ Abstract |
Background |
This study aimed to evaluate whether lower extremity (LE) amputation among civilian casualties is a risk factor for venous thromboembolism.
Methods |
All patients with severe LE injuries (AIS ≥3) derived from the ACS-TQIP (2013–2020) were divided into those who underwent trauma-associated amputation and those with limb salvage. Propensity score matching was used to mitigate selection bias and confounding and compare the rates of pulmonary embolism (PE) and deep vein thrombosis (DVT).
Results |
A total of 145,667 patients with severe LE injuries were included, with 3443 patients requiring LE amputation. After successful matching, patients sustaining LE amputation still experienced significantly higher rates of PE (4.2% vs. 2.5%, p < 0.001) and DVT (6.5% vs. 3.4%, p < 0.001). A sensitivity analysis examining patients with isolated major LE trauma similarly showed a higher rate of thromboembolic complications, including higher incidences of PE (3.2% vs. 2.0%, p = 0.015) and DVT (4.7% vs. 2.6%, p < 0.001).
Conclusions |
In this nationwide analysis, traumatic lower extremity amputation is associated with a significantly higher risk of VTE events, including PE and DVT.
Le texte complet de cet article est disponible en PDF.Graphical abstract |
Highlights |
• | Traumatic lower extremity amputation and the risk of venous thromboembolism. |
• | Pulmonary embolism and deep vein thrombosis were more prevalent in traumatic amputees. |
• | Traumatic amputation as a newly uncovered risk factor for VTE – scoring systems research. |
Keywords : Traumatic amputation, Venous thromboembolism, Prophylaxis
Plan
Vol 232
P. 95-101 - juin 2024 Retour au numéro
Article précédent
- Development and validation of prealbumin-bilirubin score (preALBI score) for predicting long-term survival after hepatectomy for hepatocellular carcinoma: A multicenter analysis versus ALBI score
- Chao Li, Ming-Da Wang, Xiao-Dong Sun, Yong-Kang Diao, Lan-Qing Yao, Hong Wang, Ying-Jian Liang, Ya-Hao Zhou, Wei-Min Gu, Ting-Hao Chen, Zhong Chen, Li-Hui Gu, Feng Shen, Guo-Yue Lv, Tian Yang, Dong-Sheng Huang
- Effect of Medicaid expansion on inflammatory bowel disease and healthcare utilization
- Brittany E. Levy, Anthony A. Mangino, Jennifer T. Castle, Wesley A. Stephens, Hannah G. McDonald, Jitesh A. Patel, Sandra J. Beck, Avinash S. Bhakta
Bienvenue sur EM-consulte, la référence des professionnels de santé.
L’accès au texte intégral de cet article nécessite un abonnement.
Déjà abonné à cette revue ?