The complex link between sleep-disordered breathing and asthma control in pediatric patients: A cross-sectional study - 02/08/24
, Mariangela V. Puci b, Laura Saderi b, Giovanni Sotgiu b, Caterina Zanza a, Roberto Antonucci aAbstract |
Background |
In children, asthma and sleep-disordered breathing (SDB) may affect quality of life (QoL), and SDB may complicate asthma management.
Objective |
To evaluate the prevalence of SDB, its association with asthma control, and risk factors associated with SDB in a cohort of asthmatic children. The effects of asthma control and SDB on QoL were also investigated.
Methods |
We consecutively recruited asthmatic children referred to our Pulmonology Service from December 1, 2022 to May 31, 2023. Data on anthropometrics, respiratory function, and allergies were collected. The prevalence of SDB was assessed by the Pediatric Sleep Questionnaire (PSQ). Asthma control status was assessed by the Childhood Asthma Control Test (C-ACT), while QoL was evaluated by the Pediatric Quality of Life Inventory (PedsQL) questionnaire. Factors associated with SDB were analyzed.
Results |
A total of 78 asthmatic children aged 5–12 years were included. SDB was found in 37.2% of them, with a higher prevalence in children with uncontrolled versus well-controlled asthma (60.1% vs. 27.3%; p-value = 0.005). The C-ACT score was significantly lower in SDB-positive versus SDB-negative group, and uncontrolled asthma (C-ACT ≤19) was associated with a 4.15-fold increased risk of SDB. The PedsQL score was significantly lower in asthmatic children with than without SDB and was associated with lower SDB risk. SDB increased the risk of uncontrolled asthma in children, and asthmatic children with SDB had lower QoL.
Conclusion |
In asthmatic children, SDB affects both asthma control and QoL. Children with uncontrolled asthma should be referred for polysomnography to identify a possible underlying SDB.
Le texte complet de cet article est disponible en PDF.Graphical abstract |
Highlights |
• | SDB and asthma are highly prevalent respiratory diseases with a bidirectional relationship and overlapping symptoms. |
• | SDB may lead to reduced asthma control and predict the severity of asthma in children. |
• | SDB was associated with a 4.15-fold increased risk of uncontrolled asthma, and QoL was lower in asthmatic children with SDB. |
Keywords : Asthma, Sleep-disordered breathing, Obstructive sleep apnea, Quality of life, Children
Plan
Vol 231
Article 107730- septembre 2024 Retour au numéro
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