Trends in thyroid function following radiofrequency ablation of benign, nonfunctioning thyroid nodules: A single institution review - 26/09/24

Abstract |
Background |
Radiofrequency ablation (RFA) effectively reduces volume and improves symptoms of benign, non-functioning thyroid nodules (NFTNs). Given RFA's unclear impact on thyroid function, we examined post-RFA trends in thyroid hormones and antibodies.
Methods |
A retrospective cross-sectional analysis was conducted of patients treated at Columbia University with RFA for benign NFTNs between August 2019 and July 2023. Thyroid function tests were recorded pre-RFA and repeated 3, 6, and 12 months post-RFA.
Results |
We analyzed 185 patients with 243 benign NFTNs who underwent RFA. Volume reduction ratio increased post-RFA. Mean TSH increased to 2.4 mlU/L (p = 0.005) at 3 months post-RFA and decreased to 1.8 mlU/L (p = 0.551) by 12 months post-RFA. Tg and TPO antibody levels peaked at 6 months post-RFA (103.1 IU/mL, p = 0.868 and 66.6 IU/mL, p = 0.523, respectively).
Conclusions |
With expected volume reduction post-RFA, we observed transient relative hypothyroidism as well as transient increases in thyroid antibodies, with normalization of these changes within 12 months.
Le texte complet de cet article est disponible en PDF.Highlights |
• | Transient relative hypothyroidism observed at 3 months after RFA of NFTNs. |
• | Transient increases in thyroid antibodies peaked at 6 months after RFA of NFTNs. |
• | Long-term normalization of thyroid hormone and antibody changes. |
Keywords : Radiofrequency ablation, Thyroid nodules, Thyroid function tests
Plan
Vol 237
Article 115793- novembre 2024 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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