Obesity Definitions in Sarcopenic Obesity: Differences in Prevalence, Agreement and Association with Muscle Function - 21/11/24
, J.P. Lim 2, 3, L. Tay 4, A. Yeo 3, S. Yew 3, Y.Y. Ding 2, 3, W.S. Lim 2, 3
Bienvenue sur EM-consulte, la référence des professionnels de santé.
Article gratuit.
Connectez-vous pour en bénéficier!
Abstract |
Background |
Sarcopenic obesity (SO) is associated with poorer physical performance in the elderly and will increase in relevance with population ageing and the obesity epidemic. The lack of a consensus definition for SO has resulted in variability in its reported prevalence, poor inter-definitional agreement, and disagreement on its impact on physical performance, impeding further development in the field. While sarcopenia definitions have been compared, the impact of obesity definitions in SO has been less well-studied.
Objectives |
To compare 3 widely-adopted definitions of obesity in terms of SO prevalence, inter-definitional agreement, and association with muscle function.
Design |
Cross-sectional.
Setting |
GERILABS study, Singapore
Participants |
200 community-dwelling, functionally-independent older adults.
Measurements |
We utilized three commonly-used definitions of obesity: body mass index (BMI), waist circumference (WC) and DXA-derived fat mass percentage (FM%). Sarcopenia was defined using Asian Working Group for Sarcopenia criteria. For muscle function, we assessed handgrip strength, gait speed and Short Physical Performance Battery (SPPB). Subjects were classified into 4 body composition phenotypes (normal, obese, sarcopenic and SO), and outcomes were compared between groups.
Results |
The prevalence rate for SO was lowest for BMI (0.5%) compared to FM% (10.0%) and WC (10.5%). Inter-definitional agreement was lowest between BMI and WC (κ=0.364), and at best moderate between FM% and WC (κ=0.583). SO performed the worst amongst body composition phenotypes in handgrip strength, gait speed and SPPB (all p<0.01) only when defined using WC. In regression analyses, SO was associated with decreased SPPB scores (β=−0.261, p=0.001) only for the WC definition.
Conclusion |
There is large variation in the prevalence of SO across different obesity definitions, with low-to-moderate agreement between them. Our results corroborate recent evidence that WC, and thus central obesity, is best associated with poorer muscle function in SO. Thus, WC should be further explored in defining obesity for accurate and early characterization of SO among older adults in Asian populations.
Le texte complet de cet article est disponible en PDF.Key words : Sarcopenic obesity, definition, agreement, waist circumference, muscle function
Plan
| Electronic Supplementary Material Supplementary material is available for this article at jfa.2019.28 and is accessible for authorized users. |
Vol 9 - N° 1
P. 37-43 - janvier 2020 Retour au numéro
Article précédent
- Neuromuscular Attributes are Associated with Poor Mobility in Older Adults with Vascular Risk Conditions
- Azizah J. Jor’dan, M.E. Jacob, E. Leritz, J.F. Bean
- The Use of Posturography in Investigating the Risk of Falling in Frail or Prefrail Older People with Diabetes
- Hélène Domergue, L. Rodríguez-Mañas, O. Laosa Zafra, K. Hood, D. Gasq, S. Regueme, A.J. Sinclair, I. Bourdel-Marchasson
Bienvenue sur EM-consulte, la référence des professionnels de santé.