Peri-implant diseases require an extensive approach that includes pre-operative risk assessment, patient education on oral hygiene, and ensuring sufficient tissue support and accurate implant placement. Treatment typically starts with comprehensive decontamination using mechanical debridement, chemical agents, and advanced therapies such as laser or photodynamic therapy. Depending on the severity of the disease and the extent of bone loss, surgical strategies are adapted, ranging from less invasive access surgery in initial stages to more intensive resective or regenerative procedures in advanced cases. The following article will present a holistic and systematic approach to managing periimplantitis.