How do residential aged care antibiograms compare with other local resistance data? - 25/12/24
, Nazanin Falconer, PhD b, Sonali Coulter, PhD c, Leonard C. Gray, MBBS, PhD a, David L. Paterson, MBBS, PhD d, e, Christopher Freeman, PhD b, d, fCet article a été publié dans un numéro de la revue, cliquez ici pour y accéder
Résumé |
Background |
Antibiograms can optimize empirical antibiotic prescribing; however, they are not readily available for residential aged care facilities (RACFs) in Queensland, Australia. This study aimed to determine whether alternatively available data can be used to approximate resistance patterns for RACFs.
Methods |
Annual RACF-specific antibiograms were compared with local hospital antibiograms accessed through pathology providers. Additionally, composite antibiograms, of geographically united RACF data, were compared with regional hospital and private pathology RACF antibiograms. Antibiotic susceptibility rates for commonly observed bacteria (Escherichia coli, Klebsiella pneumonia, Enterococcus faecalis, Pseudomonas aeruginosa, and Staphylococcus aureus) were compared among different antibiograms using Fisher exact test, with a P value ≤ 0.05 indicating the statistically significant difference. The concordance among the antibiograms was described by percentage similarity overall and for a subset of clinically relevant pathogen-antibiotic pairs.
Results |
Composite RACF antibiogram was highly concordant (83%-100% similarity) to private pathology RACF data when compared for clinically relevant pathogen-antibiotic pairs. Mixed results were found when individual RACF-specific antibiograms were compared with local hospital all-ages and ≥ 65 years data (50%-100% and 67%-100% similarity, respectively).
Conclusions |
Private pathology RACF antibiograms can serve as a proxy indicator of resistance patterns for RACFs. Mixed findings were noted for comparisons with hospital data.
Le texte complet de cet article est disponible en PDF.Highlights |
• | Antibiograms are not readily available for residential aged care facilities (RACFs). |
• | Alternatively available data as a proxy for resistance patterns in RACFs have been studied. |
• | Private pathology data originating from RACFs is concordant with RACF antibiograms. |
• | Mixed results were found with RACF antibiogram and nearby hospital comparisons. |
Key Words : Cumulative susceptibility, Nursing home, Empirical antibiotics
Plan
| Funding/support: This work has been funded by the University of Queensland Research Training Program scholarship (DK) and Medical Research Future Fund 2017/MRF1152503 (DP, LG, and CF). |
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| Conflicts of interest: None to report. |
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