This review explores the application of gastrointestinal endoscopy in exotic animals, a field with unique challenges due to the diverse anatomic and physiologic characteristics of species such as small mammals, birds, reptiles, and amphibians. The study outlines its indications, including diagnostic and therapeutic purposes, and discusses the specific equipment and techniques required. Despite the technical difficulties and anesthesia risks associated with these procedures, gastrointestinal endoscopy remains a valuable tool in exotic animal medicine. Like in other diagnostic methods, the large number of species demands special knowledge of the anatomic characteristics.