Introduction: Air pollution has a significant adverse effect on the life expectancy of people worldwide. Exposure to dust storms can adversely affect health, the environment, and economic stability. Research suggests a connection between air quality and increased death rates related to heart issues. Interleukins are important in causing inflammation. This research investigates the link between the amount of PM₁₀ and interleukin-6 levels among healthy individuals in Zahedan.

Materials and method: In this study, sampling was performed using a PQ200/BGI sampler six days a week, including days with dust storms. The study assessed biomarker interleukin-6 levels in blood samples collected from 40 volunteers aged 20 to 35 years using the enzyme-linked immunosorbent assay) ELISA (method.

Results and discussion: The mean concentration of PM₁₀ in the air of Zahedan during the study period was 210.4 μg/m3, indicating elevated levels of PM₁₀, a major air pollutant, surpassing standard levels. Furthermore, the study found that interleukin 6 levels in blood samples collected during air pollution conditions were significantly higher than those in the control group (P-value<0.05).

Conclusion: When PM₁₀ concentrations exceed the standard limit, these findings emphasize the importance of prioritizing health programs, especially considering the increase in cardiovascular and respiratory diseases, as well as elevated interleukin-6 levels during dust storms.