Cold- versus hot-snare endoscopic mucosal resection of colorectal polyps: meta-analysis of randomized controlled trials - 08/05/25

Abstract |
Background and Aims |
Interest in cold endoscopic mucosal resection (EMR) for colorectal polyps has been growing. We conducted a meta-analysis of randomized controlled trials to compare cold and hot EMR for colorectal polyps.
Methods |
We reviewed several databases from inception to October 6, 2024. Outcomes of interest were recurrent or residual neoplasia, en-bloc resection, incomplete resection, perforation, and intraprocedural and delayed bleeding. Pooled risk ratios (RRs) with 95% confidence intervals (CIs) were calculated by means of a random-effects model.
Results |
Rate of recurrent or residual neoplasia was significantly higher in the cold EMR group: RR, 2.03 (95% CI, 1.19-3.48). Rates of delayed bleeding RR, 0.42 (95% CI, 0.21-0.86) and perforation RR, 0.13 (95% CI, 0.03-0.59) were significantly lower with cold EMR. We found no significant difference in other outcomes between groups.
Conclusions |
Cold EMR is associated with lower risk of delayed bleeding and perforation but higher risk of recurrent or residual neoplasia compared with hot EMR.
Le texte complet de cet article est disponible en PDF.Abbreviations : CSP, EMR, HSP, RCT, SSL, STSC, USMSTF
Plan
| DIVERSITY, EQUITY, AND INCLUSION: The author list of this paper includes contributors from the location where the research was conducted who participated in the data collection, design, analysis, and/or interpretation of the work. |
Vol 101 - N° 6
P. 1239 - juin 2025 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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