Dynamic global variation in resistance and hypervirulence of carbapenem-resistant Klebsiella pneumoniae between 2010 and 2023 - 22/05/25
Doi : 10.1016/j.jinf.2025.106493
Zhang Feilong
Peking Union Medical College, Chinese Academy of Medical Sciences, China-Japan Friendship Hospital, Beijing, China
Lu Binghuai ⁎ 
Peking Union Medical College, Chinese Academy of Medical Sciences, China-Japan Friendship Hospital, Beijing, China
Peking University China-Japan Friendship School of Clinical Medicine, Beijing, China
∗Correspondence to: Peking Union Medical College, Chinese Academy of Medical Sciences, China-Japan Friendship Hospital, No. 2 East Yinghua Street, Chaoyang District, Beijing 100029, China.Peking Union Medical College, Chinese Academy of Medical Sciences, China-Japan Friendship HospitalNo. 2 East Yinghua Street, Chaoyang DistrictBeijing100029China
Cao Bin ⁎
Peking Union Medical College, Chinese Academy of Medical Sciences, China-Japan Friendship Hospital, Beijing, China
∗∗Correspondence to: Peking Union Medical College, Chinese Academy of Medical Sciences, China-Japan Friendship Hospital, No. 2 East Yinghua Street, Chaoyang District, Beijing 100029, China.Peking Union Medical College, Chinese Academy of Medical Sciences, China-Japan Friendship HospitalNo. 2 East Yinghua Street, Chaoyang DistrictBeijing100029China
Highlights |
• | 26,713 CRKP genomes with spatiotemporal metadata from 90 countries were selected for genomic analysis. |
• | Global CRKP presented divergent trends in resistance and hypervirulence between before and during the COVID-19 pandemic. |
• | Substantial interregional molecular heterogeneity existed. |
• | Isolation of non-clinical CRKP underscored the importance of One Health-driven surveillance. |
Plan
© 2025
The Author(s). Publié par Elsevier Masson SAS. Tous droits réservés.
Vol 90 - N° 6
Article 106493- juin 2025 Retour au numéro
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