Implementing a Uniform Outcome Measurement Approach for Early Interventions of Autism Spectrum Disorders - 28/05/25
Abstract |
Objective |
Naturalistic developmental behavioral interventions for children with autism spectrum disorder show evidence for effectiveness for specific social communication targets such as joint attention or engagement. However, combining evidence from different studies and comparing intervention effects across those studies have not been feasible due to lack of a standardized outcome measure of broader social communication skills that can be applied uniformly across trials. This investigation examined the usefulness of the Brief Observation of Social Communication Change (BOSCC) as a common outcome measure of general social communication skills based on secondary analyses of data obtained from previously conducted randomized controlled trials of 3 intervention models, Early Social Intervention (ESI), Early Start Denver Model (ESDM) and Joint Attention Symbolic Play Engagement and Regulation (JASPER).
Method |
The subset of datasets from the 3 randomized controlled trials was created to examine differences in the BOSCC scores between intervention and control groups over the course of the interventions.
Results |
Based on 582 videos from 207 caregiver–child dyads, the BOSCC noted significant differences between intervention vs control groups in broad social communication skills within 2 of the 3 intervention models, which were longer in duration and focused on a broad range of developmental skills.
Conclusion |
The BOSCC offers the potential to take a uniform measurement approach across different intervention models to capture the effect of intervention on general social communication skills but may not pick up the effects of some brief interventions targeting proximal outcomes.
Plain language summary |
Discovering effective interventions for children with autism spectrum disorder (ASD) is crucial, but comparing their outcomes has been challenging due to a lack of standardized measures. This study investigated the Brief Observation of Social Communication Change (BOSCC) as a common metric for evaluating general social communication skills across different interventions. Analyzing data from 3 randomized control trials, researchers found significant improvements in broad social communication skills within two of the interventions. The BOSCC shows promise as a tool for assessing the impact of longer, comprehensive interventions on social communication skills.
Clinical trial registration information |
Comparing Parent-Implemented Interventions for Toddlers With Autism Spectrum Disorders; NCT00760812. Intensive Intervention for Toddlers With Autism (EARLY STEPS); NCT00698997. Social and Communication Outcomes for Young Children With Autism; NCT00953095.
Le texte complet de cet article est disponible en PDF.Key words : autism spectrum disorders, early intervention, outcome measures
Plan
| The study was funded by the NIMH (R01MH114925; PI Kim), NIMH/NICHD (R01081757; PI Rogers), HRSA/AIR-B (UA3MC11055; PI Kasari), SFARI (PIs Kim and Lord), and the Korean Ministry of Science and ICT of the National Research Foundation of Korea (RS-2023-00209635, PI Kim; 2023S1A5C2A0709598711, Co-I Kim; RS-2024-00398768, Co-I Kim). |
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| The research was performed with permission from the Weill Cornell Medicine and Korea Unviersity IRBs. |
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| The manuscript was based on a secondary data analysis that pulled data from previously conducted randomized controlled trials. The original study sites created their own documentation, which included that the data will be used for future research. The data sharing between sites for the current study was approved by Weill Cornell Medicine IRB, but the original consent forms were not obtained. |
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| Data may be shared upon request per IRB regulations. |
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| Eva Petkova served as the statistical expert for this research. |
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| The authors thank Hannah Thomas, MS, at the University of Connecticut, Claire Klein, MA, at the University of North Carolina, and Elysha Clark Whitney, MCP, at the University of Sydney, for their contribution with data collection. |
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| Disclosure: Catherine Lord has received royalties from Western Psychological Services for publication of the Autism Diagnostic Observation Schedule (ADOS). Royalties related to this study were donated to a charity. Sally J. Rogers has reported being a developer of the Early Start Denver Model (ESDM) and has received royalties from the sale of the published ESDM materials. Connie Kasari has reported being a developer of the Joint Attention Symbolic Play Engagement and Regulation (JASPER). So Hyun Kim has received consultation fees from Neudive for work unrelated to the current study. Deanna Swain, Yi Li, Hallie R. Brown, Eva Petkova, Annette Estes, and So Hyun Kim have reported no biomedical financial interests or potential conflicts of interest. |
Vol 64 - N° 6
P. 699-709 - juin 2025 Retour au numéro
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