Scalp cooling for preventing persistent chemotherapy-induced alopecia in anthracycline-treated patients: A single-arm trial - 02/07/25

Doi : 10.1016/j.jaad.2025.06.023

Danbee Kang, PhD ^a,^b, Haseen Lee, BS ^a,^b, Di Zhao, PhD ^c,^d, Nayeon Kim, MSN ^a,^e, Hoyoung Kim, MPH ^e, Sooyeon Kim, BS ^a,^b, Ji-Yeon Kim, MD, PhD ^f, Yeon Hee Park, MD, PhD ^f, Hee-Kyung Ahn, MD, PhD ^f, Eliseo Guallar, MD, DrPH ^a,^b,^c,^d, Juhee Cho, PhD ^a,^b,^⁎ , Jin Seok Ahn, MD, PhD ^f,^⁎
^a Department of Clinical Research Design and Evaluation, SAIHST, Sungkyunkwan University, Seoul, Republic of Korea
^b Center for Clinical Epidemiology, Research Institute for Future Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea
^c Department of Epidemiology, School of Global Public Health, New York University, New York, New York
^d Department of Medicine and Welch Center for Prevention, Epidemiology and Clinical Research, Johns Hopkins Medical Institutions, Baltimore, Maryland
^e Cancer Education Center, Samsung Comprehensive Cancer Center, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea
^f Division of Hematology/Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea

^∗Correspondence to: Juhee Cho, PhD, Department of Clinical Research Design and Evaluation, SAIHST, Sungkyunkwan University, 81 Irwon-ro, Gangnam-Gu, Seoul 06351, South KoreaDepartment of Clinical Research Design and EvaluationSAIHSTSungkyunkwan University81 Irwon-roGangnam-GuSeoul06351South Korea^∗∗Correspondence to: Jin Seok Ahn, MD, PhD, Division of Hematology/Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-Gu, Seoul 06351, Republic of KoreaDivision of Hematology/OncologyDepartment of MedicineSamsung Medical CenterSungkyunkwan University School of Medicine81 Irwon-ro, Gangnam-GuSeoul06351Republic of Korea

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Key words : a single-arm trial, alopecia, anthracycline-treated patients, breast cancer, preventing chemotherapy-induced alopecia, scalp cooling

	Drs Cho and Ahn contributed equally to this work as corresponding authors.
	Funding sources: This study was supported by Paxman. The funding source had no role in the study design, data collection, data analysis, data interpretation, writing of the scientific article, or the decision to submit the paper for publication.
	Patient consent: Each patient provided informed consent.
	IRB approval status: Reviewed and approved by the Institutional Review Board of Samsung Medical Center IRB; No. 2019-12-148.

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Scalp cooling for preventing persistent chemotherapy-induced alopecia in anthracycline-treated patients: A single-arm trial - 02/07/25

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