Editorial: Exploring Rare Genetic Variation in Pediatric-Onset Obsessive-Compulsive Disorder: Some Excitement and Some Uncertainty - 25/07/25
Doi : 10.1016/j.jaac.2025.06.009
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Disponible en ligne depuis le Friday 25 July 2025
Résumé |
Genetic factors play a central role in the risk for developing obsessive-compulsive disorder (OCD), a finding established through twin, family, and large-scale cohort studies. Current genetic research aims to identify the specific genetic and genomic variants contributing to OCD risk.1 This involves investigating both common genetic variation—studied through genome-wide association studies (GWAS)—and rare genetic and genomic variation—studied through genome/exome sequencing or chromosomal microarray.
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| Dorothy E. Grice is the recipient of support from National Institutes of Health (NIH) R01 MH124679, NIH R01 MH136218, the International OCD Foundation Innovator Award, and the Beatrice and Samuel A. Seaver Foundation. |
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| Disclosure: Dorothy E. Grice has reported no biomedical financial interests or potential conflicts of interest. |
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| All statements expressed in this column are those of the authors and do not reflect the opinions of the Journal of the American Academy of Child and Adolescent Psychiatry. See the Guide for Authors for information about the preparation and submission of Editorials. |
© 2025
American Academy of Child and Adolescent Psychiatry. Publié par Elsevier Masson SAS. Tous droits réservés.
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