Temporal muscle thickness predicts change in nutritional markers in individuals at risk of dementia: Insights from a 24-week longitudinal study - 09/08/25
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NJ FINGER
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Highlight |
• | In patients in the spectrum of cognitive decline, it is important to consider outcomes beyond cognition, such as nutritional status. |
• | At follow-up, temporal muscle thickness was associated with albumin levels and weight. |
• | Temporal muscle thickness is a widely available biomarker, that could possibly be a tool for the assessment of patients beyond cognition. |
Abstract |
Objectives |
To investigate whether temporal muscle thickness (TMT) can serve as a predictor of change in nutritional widely used biomarkers in patients at risk of dementia.
Design |
Longitudinal observational study.
Setting |
Secondary analysis from a 24-week study conducted across three centers in Norway between 2018 and 2020.
Participants |
Patients with mild cognitive impairment (MCI) or with two cardiometabolic disorders were included ( n = 165).
Measurements |
Baseline and longitudinal statistical analysis were carried out to establish the association for outcomes (albumin, weight, C-Reactive Protein and Episodic Memory Quality) with TMT.
Results |
At baseline, there was a positive association between TMT and weight (Estimate=1.5157, p = 0.009). At follow-up, positive associations were observed between TMT and albumin levels (Estimate=0.3031, P = 0.048), as well as TMT and weight (Estimate=1.8954, P = 0.001).
Conclusion |
TMT is a possible accessible tool in clinical practice for monitoring health variables beyond cognitive decline in patients at risk of dementia.
Le texte complet de cet article est disponible en PDF.Keywords : Cognitive dysfunction, Heart disease risk factors, Temporal muscle, Nutritional status
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Vol 14
Article 100023- 2025 Retour au numéro
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