Computed tomography for the diagnosis of HIV-associated gastro-intestinal histoplasmosis - 03/09/25
, Lorenzo Garzelli a, b, Ugo Françoise b, c, d, e, Alolia Aboikoni e, f, Antoine Adenis b, c, d, e, Magaly Zappa a, b, eHighlights |
• | Disseminated histoplasmosis is a major cause of death among PLHIV in Latin America but is still underestimated and misdiagnosed. |
• | CT aspects of intestinal histoplasmosis were thickening of the colonic wall associated with peri digestive fat stranding and lymphadenopathy. |
• | The most commonly affected segments were the caecum and right colon. |
• | These scanographic features could lead to an early diagnosis in patients with advanced HIV disease in the absence of proven histoplasmosis. |
Abstract |
Introduction |
Disseminated histoplasmosis is one of the leading opportunistic infections among people living with human immunodeficiency virus (PLHIV) in Latin America. Intestinal involvement is common, but its computed tomography findings have not been properly described. We aimed to provide a computed tomography description of histoplasmosis intestinal involvement.
Patients and methods |
We performed a retrospective observational study of patients with disseminated histoplasmosis and proven intestinal involvement.
Results |
A total of 18 patients with an available contrast-enhanced abdominal computed tomography (8 women, mean age 44 years) were included. Seventeen had intestinal parietal thickening (94 %), with a mean thickening of 14 mm, unifocal or multifocal, frequently circumferential (71 %). The most commonly affected segments were the cecum and right colon in 13/17 (76 %) of patients each. Adenomegaly was constant, mostly homogeneous.
Conclusion |
These computed tomography features in patients with advanced HIV disease may be key findings for an early diagnosis in the absence of proven histoplasmosis.
Le texte complet de cet article est disponible en PDF.Keywords : Computed tomography scanner, Disseminated histoplasmosis, Gastrointestinal diseases, HIV, HIV-related opportunistic infection
Plan
Vol 55 - N° 6
Article 105105- septembre 2025 Retour au numéro
Article précédent
- Appropriateness of piperacillin-tazobactam prescriptions: a prospective multicentre study
- Pierre-Marie Roger, Catherine Lechiche, Pauline Quint, Agnès Simand, Jacques Roghi, Sylvie Comparot, Marc-Antoine Hennet, Catherine Beranger, Pierre Mignonat, Laure Belmondo, Eric Denes
- Epidemiological changes in the incidence of human leptospirosis in Thailand: Findings from the National Disease Surveillance System from 2013 to 2022
- Chanasan Sawangpol, Natnaree Aimyong, Arthit Phosri
Bienvenue sur EM-consulte, la référence des professionnels de santé.
L’accès au texte intégral de cet article nécessite un abonnement.
Déjà abonné à cette revue ?