NICU-specific bundle for minimizing central line-associated bloodstream infections: Comparative health care costs of interventions - 13/09/25
Résumé |
Background |
Central line-associated bloodstream infections (CLABSIs) in neonatal intensive care units (NICUs) significantly impact patient outcomes and health care costs. This study evaluates the effect of NICU-specific bundle designed to prevent CLABSIs.
Methods |
This retrospective single-center study was conducted at Hacettepe University Faculty of Medicine from March 2020 to August 2021. It was designed to compare 2 periods: pre-intervention and post-intervention period.
Results |
The implementation of the bundles led to a significant reduction in infection rates, with CLABSIs decreasing from 29 to 4 per 1,000 central line days in NICU-1 and from 14.2 to 2.6 per 1,000 central line days in NICU-2. This decline was accompanied by an 80% reduction in the average health care cost per patient.
Conclusions |
The implementation of a NICU-specific CLABSI prevention bundle significantly reduced infection rates and lowered health care costs by approximately 80% per patient. These findings highlight the effectiveness of structured, multidisciplinary infection control strategies in improving neonatal outcomes and resource utilization.
Le texte complet de cet article est disponible en PDF.Highlights |
• | NICU-specific bundle reduced infection rates by over 80%. |
• | Central line days and total health care costs decreased significantly. |
• | Preterm-specific modifications improved bundle safety and feasibility. |
• | Multidisciplinary approach enhanced bundle adherence and sustainability. |
Key Words : Neonatal, Bundle, Infection control, Healthcare cost, Central venous catheter, Quality improvement
Plan
| Conflicts of interest: None to report. |
Vol 53 - N° 10
P. 1085-1090 - octobre 2025 Retour au numéro
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