Cervicogenic headache (CGH) has proven to be an elusive diagnosis without the aid of diagnostic interventional procedures. This article highlights the key components of the clinical presentation and workup to aid the clinician in distinguishing CGH from its differential diagnoses. It also discusses the evidence and outcomes behind the treatment options to guide physicians when establishing a plan for patients. Fortunately, most cases will resolve with conservative care and physical therapy, but severe or chronic cases will likely require the expertise of an interventional spine physician or surgeon.