Autism affects 2% to 3% of youth, approximately half of whom experience a co-occurring anxiety disorder. Left untreated, anxiety symptoms show a worsening trajectory into adulthood and increase the functional impact of the core autism symptoms. Innovative treatment approaches such as Internet-CBT adapted for autistic youth demonstrate preliminary effectiveness in symptom reduction while overcoming barriers and increasing accessibility. Insights and considerations regarding the development of the Learning to Understand and Navigate Anxiety for Adolescents (LUNA-Adolescent) program are presented as a promising approach to treatment for autistic adolescents and their families.