This article reviews metabolic alkalosis in small animals, a condition characterized by increased blood pH and elevated serum bicarbonate, most commonly resulting from vomiting, diuretic therapy, or hypoalbuminemia. It differentiates between chloride-responsive and chloride-resistant forms and emphasizes the importance of identifying and addressing the underlying cause. Management focuses on fluid therapy and correction of electrolyte abnormalities, particularly chloride and potassium. Careful monitoring and restoration of circulatory volume and electrolyte balance are essential to reestablish normal acid-base status and prevent complications.