Müller-Weiss disease (MWD) is generally identified by deformity, sclerosis, and fragmentation of the navicular bone. Characteristically, the navicular is comma shaped with varying degrees of arthritis in the talonavicular and naviculocuneiform joints. It is usually asymptomatic for several years before presenting as dorsal foot pain. Operative management is indicated for symptoms persisting after failure of conservative treatment. Arthrodesis of the talonavicular, triple, or TNC joints and calcaneal osteotomy can be performed. A lateralizing Dwyer-type calcaneal osteotomy appears to be useful in early MWD cases with limited arthritis of the medial column and associated subtalar or heel varus.