In this article, the authors review the potential influence and benefits of artificial intelligence (AI) in orthodontics and dentofacial orthopedics with particular emphasis on current applications and emerging developments. Specific focus areas such as diagnosis, growth evaluation, treatment planning, personalized care, robotic technologies, virtual surgical planning, and improvements in clinical workflow will be explored. The review showcases evidence of AI leading to increased accuracy in diagnosis, supplementing clinical decision making, and ultimately improving the overall clinical experience. As the authors highlight the practical and innovative applications of AI, certain ethical implications are also discussed.