^a Department of Medical Sciences, Clinical Physiology, Uppsala University, Uppsala, Sweden 

^b Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden 

^c Karolinska Severe Asthma Center, Department of Respiratory Medicine and Allergy, Karolinska University Hospital, Stockholm, Sweden 

^d Division of Lung and Airway Research, Institute of Environmental Medicine, Karolinska Institutet, and Center for Molecular Medicine, Stockholm, Sweden 

^e Lung Laboratory, Centre for Molecular Medicine, Karolinska University Hospital, Stockholm, Sweden 

^f Region Västra Götaland, Sahlgrenska University Hospital, Department of Clinical Physiology, Gothenburg, Sweden 

^g Department of Clinical Physiology, Karolinska University Hospital, and Karolinska Institutet, Stockholm, Sweden 

^h Section of Occupational and Environmental Medicine, School of Public Health and Community Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden 

ⁱ Department of Clinical Sciences Lund, Respiratory Medicine, Allergology and Palliative Medicine, Lund University, Lund, Sweden 

^j Department of Clinical Physiology, and Department of Health, Medicine, and Caring Sciences, Linköping University, Linköping, Sweden 

^k CMIV, Centre of Medical Image Science and Visualization, Linköping University, Linköping, Sweden 

^l Centre for Sleep and Vigilance Disorders, Department of Internal Medicine and Clinical Nutrition, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden 

^m Sleep Disorders Centre, Pulmonary Medicine, Sahlgrenska University Hospital, Gothenburg, Sweden 

ⁿ Region Västra Götaland, Sahlgrenska University Hospital, Department of Clinical Genetics and Genomics, Gothenburg, Sweden 

^o Department of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden 

^p Department of Clinical Sciences, Lund University and Department of Cardiology, Skåne University Hospital, Malmö, Sweden 

^q Department of Medical Sciences, Respiratory, Allergy and Sleep Research, Uppsala University, Uppsala, Sweden 

^r Department of Health, Medicine and Caring Sciences and Department of Clinical Physiology and Wallenberg Centre for Molecular Medicine, Linköping University, Linköping, Sweden 

^s Karolinska Severe COPD Center, Department of Respiratory Medicine and Allergy, Karolinska University Hospital, Stockholm, Sweden 

^t Department of Health, Medicine and Caring Sciences, Linköping University, Linköping, Sweden 

^u Department of Respiratory Medicine in Linköping, Linköping University, Linköping, Sweden 

^v Division of Immunology and Respiratory Medicine, Department of Medicine, Karolinska Institutet, Solna, Stockholm, Sweden 

^w Department of Respiratory Medicine and Allergy, Karolinska University Hospital, Stockholm, Sweden 

^x COPD Center, Department of Internal Medicine and Clinical Nutrition, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden