Cleft Lip : Early Primary Repair - 14/05/26

Doi : 10.1016/j.coms.2026.02.004

Anika Y. Kim, MS ^a,^b, Joseph M. Firriolo, MD ^a,^b, Caroline C. Kreh, BS ^a, William P. Magee, DDS, MD ^a,^b, Jeffrey A. Hammoudeh, DDS, MD ^a,^b,^⁎

^a Children’s Hospital Los Angeles, Division of Plastic and Maxillofacial Surgery, Los Angeles, CA, USA

^b Division of Plastic and Reconstructive Surgery, Keck School of Medicine of University of Southern California, Los Angeles, CA, USA

^∗ Corresponding author. Divsion of Plastic and Maxillofacial Surgery, Children's Hospital Los Angeles, 4650 Sunset Boulevard, MS #96, Los Angeles, CA 90027. Divsion of Plastic and Maxillofacial Surgery Children's Hospital Los Angeles 4650 Sunset Boulevard MS #96 Los Angeles CA 90027

Résumé

This article synthesizes over a decade of institutional experience with more than 300 patients undergoing early cleft lip repair (ECLR) and presents a standardized, multidisciplinary framework encompassing patient selection, nutritional optimization, neonatal anesthesia, and refined operative technique. This article povides a practical, evidence-based roadmap for implementing neonatal cleft lip repair within a modern craniofacial program. By detailing selection criteria, perioperative workflows, and technical considerations, we offer a reproducible model that other institutions may adapt to their own resources and patient populations. ECLR has the potential to meaningfully reduce the cumulative surgical, financial, and psychosocial burden of cleft lip management.

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Keywords : Early cleft lip repair, Institutional algorithm, Surgical timing, Modified anatomic subunit approximation technique