This paper focuses on the detection and spatial characterization of microtopographic relief linked to archaeological remains using full-waveform (FW) Airborne Laser Scanning (ALS). ALS is an optical measurement technique for obtaining high-precision information on the Earth’s surface including basic terrain mapping, such as Digital Terrain Model (DTM) and Digital Surface Model (DSM). In the field of cultural heritage management, ALS can provide detailed information useful for feature extraction, but the detection of archaeological microtopographic relief is still a challenge especially for vegetated and highly sloped areas. The investigation was carried out for the archaeological area of Monte Irsi (Southern Italy) characterized by dense herbaceous cover and complex topographical and morphological features, which make air/space prospection very difficult. Results from our investigations pointed out that ALS is a valuable data source to detect and map cultural features even under dense vegetation.