Verbal fluency as a possible predictor for psychosis - 11/02/10
, D.H. Nieman, P.M. Dingemans, J.R. van de Fliert, L. De Haan, D.H. Linszen| pages | 6 |
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Abstract |
Background |
Neurocognitive abnormalities are prevalent in both first episode schizophrenia patients and in ultra high risk (UHR) patients.
Aim |
To compare verbal fluency performance at baseline in UHR in patients that did and did not make the transition to psychosis.
Method |
Baseline verbal fluency performance in UHR-patients (n=47) was compared to match first episode patients (n=69) and normal controls (n=42).
Results |
Verbal fluency (semantic category) scores in UHR-patients did not differ significantly from the score in first episode schizophrenia patients. Both the UHR group (p<0.003) and the patient group (p<0.0001) performed significantly worse than controls. Compared to the non-transition group, the transition group performed worse on verbal fluency, semantic category (p<0.006) at baseline.
Conclusions |
Verbal fluency (semantic category) is disturbed in UHR-patients that make the transition to psychosis and could contribute to an improved prediction of transition to psychosis in UHR-patients.
Le texte complet de cet article est disponible en PDF.Keywords : Schizophrenia and psychosis, Ultra high risk, Neuropsychology, Transition to psychosis
Plan
Vol 25 - N° 2
P. 105-110 - mars 2010 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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