Evaluation of cerebrospinal fluid adenosine deaminase activity in HIV-seropositive subjects and its association with lactate dehydrogenase and protein levels - 26/04/10
Corresponding author. Fax: +55 - 3220 8018.Bienvenue sur EM-consulte, la référence des professionnels de santé.
L’accès au texte intégral de cet article nécessite un abonnement.
| pages | 4 |
| Iconographies | 2 |
| Vidéos | 0 |
| Autres | 0 |
Abstract |
The purpose of this study was to investigate the role of ADA as additional marker of HIV infection as well as its association with other biochemical markers. This study included 55 patients, 26 being diagnosed as HIV positive and 29 patients diagnosed as HIV negative. Glucose, total protein, lactate dehydrogenase, and adenosine deaminase (ADA) activity were measured on cerebrospinal fluid (CSF). ADA activity on CSF was statistically different in HIV-seropositive subjects compared with HIV-negative subjects. The sensitivity and specificity of ADA activity on CSF was 50 and 82.76%, respectively. ADA activity was positively correlated with lactate dehydrogenase and protein in patients with HIV positive and it was negatively correlated with glucose levels. ADA determination in CSF could add information about inflammatory processes in patients with HIV infection.
Le texte complet de cet article est disponible en PDF.Keywords : Adenosine deaminase, HIV, Cerebrospinal fluid, Lactate dehydrogenase, Protein
Plan
Vol 64 - N° 4
P. 302-305 - avril 2010 Retour au numéro
Article précédent
- Enhanced internalization and endosomal escape of dual-functionalized poly(ethyleneimine)s polyplex with diphtheria toxin T and R domains
- Shinji Kakimoto, Toshizumi Tanabe, Hideki Azuma, Takeshi Nagasaki
- Herpes simplex encephalitis: A recent case
- Khwaja Sami Alim, Saba Khwaja Alim
Bienvenue sur EM-consulte, la référence des professionnels de santé.
L’accès au texte intégral de cet article nécessite un abonnement.
Bienvenue sur EM-consulte, la référence des professionnels de santé.
L’achat d’article à l’unité est indisponible à l’heure actuelle.
Déjà abonné à cette revue ?