Weekly home self-assessment of RAPID-4/3 scores in rheumatoid arthritis: A 6-month study in 26 patients - 07/12/10
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Abstract |
Objectives |
To investigate whether weekly determination of Routine Assessment of Patient Index Data (RAPID) scores 3 and 4 in patients with rheumatoid arthritis (RA) improved the assessment of disease activity and detected additional activity peaks (predictive of additional structural damage).
Methods |
Each week for 6 months, 26 patients with RA completed the patient-reported outcome questionnaires RAPID-3 and RAPID-4. During the study period, the treatment regimen for RA remained unchanged in 23 of the 26 patients.
Results |
RAPID-3 was as informative as RAPID-4. Mean values were 3.85±1.66 (range: 0.72–6.85) and 3.43±1.57 (range: 0.81–6.77), respectively. The areas under the RAPID-3 score curves plotted using only the first and last weeks or all the weeks showed a statistically significant difference in 19 (73%) of the 26 patients. The difference between the highest and lowest RAPID-3 scores was greater than the clinically significant threshold of 1.2 in all 26 patients (mean difference: 2.95±0.71; range: 1.6–5.5). In 13 patients, the RAPID-3 score detected one (one patient) or several (12 patients) activity peaks. Among RAPID-3 score components, the visual analog scale (VAS) pain score had the greatest influence (37% of the total score), followed by the VAS disease-activity score (36%) then by the multidimensional Health Assessment Questionnaire score (27%). Scores were not influenced by patient mood at questionnaire completion.
Conclusion |
Self-evaluation at home using the RAPID-3 score provides additional information that should improve the accuracy of RA monitoring between physician visits and that may help to optimize visit scheduling.
Le texte complet de cet article est disponible en PDF.Keywords : Rheumatoid arthritis, RAPID-4, RAPID-3, Patient-reported outcomes, Pain, MD-HAQ
Plan
Vol 77 - N° 6
P. 582-587 - décembre 2010 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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