Pathophysiology, Classifications, and Natural History of Perthes Disease - 02/08/11
, John A. Herring, MD b, c
Corresponding author. Texas Scottish Rite Hospital for Children, 2222 Welborn Street, Dallas, TX 75219.Résumé |
Since the original reports of Legg-Calvé-Perthes disease (LCPD), much research effort has been undertaken to improve understanding of this idiopathic hip disorder. This article focuses on the current knowledge of the pathophysiology, classifications, and natural history of LCPD. Although the cause of LCPD remains largely unknown, some insight has been gained on its pathophysiology through experimental studies using animal models of ischemic necrosis. The few available clinical studies on the natural history of LCPD suggest that femoral head deformity is well tolerated in short and intermediate terms, but 50% of patients develop disabling arthritis in the sixth decade of life.
Le texte complet de cet article est disponible en PDF.Keywords : Legg-Calvé-Perthes disease, Avascular necrosis, Ischemic necrosis, Pathophysiology, Classifications, Natural History, Pediatric, Femoral Head
Plan
| No funding was received for this work. |
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| The authors have nothing to disclose. |
Vol 42 - N° 3
P. 285-295 - juillet 2011 Retour au numéro
Article précédent
- The Epidemiology and Etiology of Perthes Disease
- Daniel C. Perry, Andrew J. Hall
- Imaging in Legg-Calvé-Perthes Disease
- Alain Dimeglio, Federico Canavese
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