Immunotherapy is an excellent treatment option for a selected subset of patients with inhalant allergies. It consists of intentional serial exposures to allergens, which modulate the immune system and induce immune tolerance through down-regulating the allergic response, resulting in an overall decrease in symptoms. Immunotherapy has been shown to have long-term efficacy in the management of inhalant allergies, as reflected by diminished frequency and duration of symptoms and improved quality of life. The therapy is considered safe, with side effects limited mostly to minor local reactions, and only occasional cases of systemic adverse reactions.