Neonatal Seizures: Do They Damage the Brain? - 05/08/11
Doi : 10.1016/j.pediatrneurol.2008.10.026
Marie-Pierre Thibeault-Eybalin, MD, CM 
, Anne Lortie, MD †, Lionel Carmant, MD †, ⁎ 
Division of Pediatric Neurology, Montreal Children’s Hospital, Departments of Neurology and Neurosurgery, McGill University, Montreal, Quebec, Canada
, Anne Lortie, MD †, Lionel Carmant, MD †, ⁎ Division of Pediatric Neurology, Montreal Children’s Hospital, Departments of Neurology and Neurosurgery, McGill University, Montreal, Quebec, Canada † Centre Hospitalier Universitaire Sainte-Justine, Research Center, Université de Montréal, Montreal, Quebec, Canada
Communications should be addressed to: Dr. Carmant; Epilepsy Clinic and Epilepsy Research Group; Centre Hospitalier Universitaire Sainte-Justine; Université de Montréal; 3175 Côte-Sainte-Catherine; Montreal, Quebec H3T 1C5, Canada.Abstract |
Seizures are an early sign of brain injury in newborns. These seizures are in most cases repetitive or associated with asymptomatic electrographic seizures. Despite the relative resistance of the immature brain to seizure-induced brain damage, there is more and more evidence that neonatal seizures impair normal brain development. This review addresses the changes associated with neonatal seizures and discusses current and future potential neuroprotective strategies.
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© 2009
Elsevier Inc. Tous droits réservés.
Vol 40 - N° 3
P. 175-180 - mars 2009 Retour au numéro
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