Structure-Function–Based Quantitative Brain Image Analysis - 05/08/11
, Marie-Louise Montandon, PhD a, Frédéric Assal, MD c
Corresponding author. Division of Nuclear Medicine, Geneva University Hospital, Geneva CH-1211, Switzerland.Résumé |
Many neurodegenerative dementias produce significant alterations in the brain that are often not detectable by neurologic tests or with structural imaging. PET is ideally suited for monitoring cell/molecular events early in the course of a disease as well as during pharmacologic therapy. During the past 2 decades, molecular neuroimaging using PET and magnetic resonance (MR) has advanced elegantly and steadily gained importance in the clinical and research arenas. Software- and hardware-based multimodality brain imaging allowing the correlation between anatomic and molecular information has revolutionized clinical diagnosis and now offers unique capabilities for the clinical neuroimaging community and neuroscience researchers at large.
Le texte complet de cet article est disponible en PDF.Keywords : Image fusion, PET-MRI, Quantification, Neurodegenerative disease, Structural brain imaging, Molecular brain imaging, PET, MRI
Plan
| This work was supported by the Swiss National Science Foundation under grants SNSF 31003A-125246 and SNSF 33CM30-124114. |
Vol 5 - N° 2
P. 155-168 - avril 2010 Retour au numéro
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