Immunologic Changes in Obesity - 05/08/11
Doi : 10.1016/j.ccc.2010.06.007
Mitchell K. Craft, DO a, Mary Jane Reed, MD, FCCM, FCCP b, ⁎ 
a Division of Critical Care Medicine, Geisinger Medical Center, 100 North Academy Avenue, Danville, PA 17822, USA
b Departments of General Surgery and Critical Care Medicine, Geisinger Medical Center, Temple University Medical School, 100 North Academy Avenue, Mail Code: 20–37, Danville, PA 17822, USA
Corresponding author.Résumé |
A growing body of literature suggests multifaceted alterations to the immune function in obese patients compared with a lean cohort. Although treatment in the intensive care unit has an associated risk of infectious complications, which, if any, of these immunologic alterations are causal is unclear. Obesity clearly causes abundant alterations to the immune system. Overall, the aggregate effect seems to be chronic activation of inflammatory mediators.
Le texte complet de cet article est disponible en PDF.Keywords : Obesity, Leptin, Adiponectin, Adipocytes, Macrophage
| The authors have nothing to disclose. |
© 2010
Publié par Elsevier Masson SAS.
Vol 26 - N° 4
P. 629-631 - octobre 2010 Retour au numéro
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