Lactic Acidosis: Recognition, Kinetics, and Associated Prognosis - 06/08/11
Doi : 10.1016/j.ccc.2009.12.007
Christopher Vernon, DO a, Jennifer L. LeTourneau, DO, MCR a, b, ⁎ 
a Division of Pulmonary and Critical Care Medicine, Oregon Health & Science University, 3181 SW Sam Jackson Park Road, UHN 67, Portland, OR 97239, USA
b Pulmonary Disease Section, Portland Veterans Affairs Medical Center, 3710 SW US Veterans Hospital Road, Mailcode P3PULM, Portland, OR 97239, USA
Corresponding author. Pulmonary Disease Section, Portland Veterans Affairs Medical Center, 3710 SW US Veterans Hospital Road, Mailcode P3PULM, Portland, OR 97239.Résumé |
Lactic acidosis is a common condition encountered by critical care providers. Elevated lactate and decreased lactate clearance are important for prognostication. Not all lactate in the intensive care unit is due to tissue hypoxia or ischemia and other sources should be evaluated. Lactate, in and of itself, is unlikely to be harmful and is a preferred fuel for many cells. Treatment of lactic acidosis continues to be aimed the underlying source.
Le texte complet de cet article est disponible en PDF.Keywords : Lactic acidosis, Mitochondria, Prognosis, Critical care, Shock, Metabolic diseases
Plan
© 2010
Publié par Elsevier Masson SAS.
Vol 26 - N° 2
P. 255-283 - avril 2010 Retour au numéro
Article précédent
- Oxygen Delivery and Consumption: A Macrocirculatory Perspective
- Dane Nichols, Nathan D. Nielsen
- Mean Arterial Pressure: Therapeutic Goals and Pharmacologic Support
- David S. Shapiro, Laurie A. Loiacono
Bienvenue sur EM-consulte, la référence des professionnels de santé.
L’accès au texte intégral de cet article nécessite un abonnement.
Déjà abonné à cette revue ?