Trunk defects can be approached through a multitude of regional flaps that can be harvested from the shoulder girdle, the epigastric axis, the paraspinal region, or the pelvic girdle. The aim of the reconstruction is to provide adequate and tension-free restoration of tissue integrity with minimal functional morbidity, water- and airtight closure of cavities, and coverage of exposed vital structures. Potential donor sites should be estimated for their tissue quality and anticipated donor site morbidity. The prototypical pedicled flap has a constant, reliable anatomy; however, the pedicled flap should have a configuration that is versatile and adequate for coverage and should resist infection. Also, the surgical technique should be uncomplicated.