Hypothalamic/Pituitary Morbidity in Skull Base Pathology - 06/08/11
Doi : 10.1016/j.otc.2011.06.010
Paul Lee, MBBS, FRACP, PhD a, b, Ken K.Y. Ho, MD, FRACP a, b, c, Jerry R. Greenfield, MBBS, FRACP, PhD d, e, f, ⁎ 
a Department of Diabetes and Endocrinology, Princess Alexandra Hospital, 199 Ipswich Road, Woolloongabba, Brisbane, Queensland, Australia 4102
b School of Medicine, University of Queensland, 199 Ipswich Road, Woolloongabba, Brisbane, Queensland, Australia 4102
c Centres of Health Research, Princess Alexandra Hospital, 199 Ipswich Road, Woolloongabba, Brisbane, Queensland, Australia 4102
d Department of Endocrinology and Diabetes Centre, 390 Victoria Street, Darlinghurst, Sydney, New South Wales, Australia 2010
e Diabetes and Obesity Program, Garvan Institute of Medical Research, 384 Victoria Street, Darlinghurst, Sydney, New South Wales, Australia 2010
f Faculty of Medicine, University of New South Wales, Sydney, New South Wales, Australia 2052
Corresponding author. Department of Endocrinology, Garvan Institute of Medical Research, 384 Victoria Street, Darlinghurst, Sydney, New South Wales, Australia 2010.Résumé |
In this article the epidemiology, pathophysiology, clinical presentation, investigation, management, and prognosis of hypopituitarism and hypothalamic dysfunction, arising from skull base pathologies and treatment of these conditions, are reviewed and discussed. The clinical question: “What is the consequence of pituitary hypofunction in young patients (ie, craniopharyngioma)?” is answered based on information provided in the review.
Le texte complet de cet article est disponible en PDF.Keywords : Hypothalamic dysfunction, Hypopituitarism, Skull base, Craniopharyngioma
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© 2011
Elsevier Inc. Tous droits réservés.
Vol 44 - N° 4
P. 1005-1021 - août 2011 Retour au numéro
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