Visceral Involvements and Long-term Sequelae in Drug-induced Hypersensitivity Syndrome - 07/08/11
Doi : 10.1016/j.mcna.2010.03.004
Yoko Kano, MD, PhD ⁎ 
, Tadashi Ishida, MD, Kazuhisa Hirahara, MD, Tetsuo Shiohara, MD, PhD
, Tadashi Ishida, MD, Kazuhisa Hirahara, MD, Tetsuo Shiohara, MD, PhD Department of Dermatology, Kyorin University School of Medicine, 6-20-2 Shinkawa Mitaka, Tokyo 181-8611, Japan
Corresponding author.Résumé |
Drug-induced hypersensitivity syndrome (DIHS) is a severe systemic reaction with several herpesvirus reactivations. Multiple organ failures appear during the course of the disease. The severity of DIHS is determined by the degree of visceral involvement. Autoimmune diseases also develop several months to years after the apparent clinical resolution of DIHS.
Le texte complet de cet article est disponible en PDF.Keywords : Drug-induced hypersensitivity syndrome, Hepatitis, Limbic encephalitis, Renal dysfunction, Sclerodermoid lesion, Systemic lupus erythematosus, Type 1 diabetes mellitus, Thyroiditis
Plan
| This work was supported by Health and Labor Sciences Research Grants from the Ministry of Health, Labor and Welfare of Japan (to Japanese Research Committee on Severe Cutaneous Adverse Reaction [J-SCAR]). |
© 2010
Elsevier Inc. Tous droits réservés.
Vol 94 - N° 4
P. 743-759 - juillet 2010 Retour au numéro
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