von Willebrand Disease - 07/08/11
Doi : 10.1016/j.pcl.2008.01.008
Jeremy Robertson, MD a, David Lillicrap, MD b, Paula D. James, MD c, ⁎ 
a Division of Hematology/Oncology, Hospital for Sick Children, 555 University Avenue, Toronto, ON M5G 1X8, Canada
b Department of Pathology and Molecular Medicine, Richardson Labs, Queen’s University, 108 Stuart Street, Kingston, ON K7L 3N6, Canada
c Department of Medicine, Queen’s University, Room 2025, Etherington Hall, 94 Stuart Street, Kingston, ON K7l 2V6, Canada
Corresponding author.Abstract |
von Willebrand disease is a common inherited bleeding disorder and many cases are diagnosed in childhood. It has a negative impact on the quality of life of affected individuals; therefore, it is important that the condition be recognized and diagnosed. This article reviews the pathophysiology of the condition, the current classification scheme, and the available treatments, highlighting issues specific to the pediatric population.
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| JR is the 2007/2008 recipient of the Baxter BioScience Pediatric Thrombosis and Hemostasis Fellowship in the Division of Hematology/Oncology at the Hospital for Sick Children. DL holds a Canada Research Chair in Molecular Hemostasis and is a Career Investigator of the Heart and Stroke Foundation of Ontario. |
© 2008
Elsevier Inc. Tous droits réservés.
Vol 55 - N° 2
P. 377-392 - avril 2008 Retour au numéro
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