MR Imaging-Based Semiquantitative Assessment in Osteoarthritis - 08/08/11
, Ali Guermazi, MD a, c
Corresponding author. Department of Radiology, Boston University School of Medicine, 820 Harrison Avenue, FGH Building, 3rd Floor, Boston, MA 02118.Résumé |
Whole-organ semiquantitative (SQ) assessment by expert readers has become a powerful research tool in understanding the natural history of osteoarthritis (OA). SQ morphologic scoring has been applied to observational large cross-sectional and longitudinal epidemiologic studies in addition to interventional clinical trials. In comparison to quantitative and biochemical assessment of cartilage, SQ whole-organ scoring also analyzes additional joint structures that are potentially relevant as surrogate outcome measures for interventional approaches. Resources needed for SQ scoring rely on the MR imaging protocol, image quality, experience of the expert readers, method of documentation, and individual scoring system that is applied. This article discusses the different available OA whole-organ scoring systems, focusing on MR imaging of the knee, and also reviews alternative approaches.
Le texte complet de cet article est disponible en PDF.Keywords : MR Imaging, Osteoarthritis, Knee, Semiquantitative scoring, Whole-Organ Magnetic Resonance Imaging Score (WORMS), Boston Leeds Osteoarthritis Knee Score (BLOKS), Knee Osteoarthritis Scoring System (KOSS), Cross-sectional and longitudinal assessment
Plan
Vol 47 - N° 4
P. 633-654 - juillet 2009 Retour au numéro
Article précédent
- MR Imaging in Osteoarthritis: Hardware, Coils, and Sequences
- Thomas M. Link
- Quantitative MR Imaging of Cartilage and Trabecular Bone in Osteoarthritis
- Felix Eckstein, Ali Guermazi, Frank W. Roemer
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