A large percentage of men are still sexually active as they age. Hence, sexual problems potentially impair men’s quality of life even in later years. Erectile dysfunction, premature ejaculation and hypogonadism are among the common sexual health problems faced by men. Published data from Asian countries demonstrate that erectile dysfunction is associated with poor quality of life in the mental and vitality domains, with increased physical co-morbidity, such as diabetes, heart diseases, prostate hyperplasia, and hyperlipidemia, and with psychological ill-health e.g. depression. A great proportion of men are also bothered by their erectile dysfunction. Although the data on premature ejaculation and hypogonadism in Asian countries are limited, there is evidence to suggest that premature ejaculation is associated with perceived low general health status, increased depression, increased anxiety, and poor mental health and vitality scores. The data also suggests that hypogonadism is associated with a number of domains in quality of life scores and depression. In conclusion, in Asian countries, erectile dysfunction, premature ejaculation and hypogonadism should be actively identified and treated to improve men’s quality of life.