Morphologic, Functional, and Metabolic Magnetic Resonance Imaging-Guided Prostate Biopsy in a Patient with Prior Negative Transrectal Ultrasound-Guided Biopsies and Persistently Elevated Prostate-Specific Antigen Levels - 09/08/11
, Philip Aschoff b, Karl Sotlar c, Susanne M. Eschmann d, Christina Pfannenberg b, Arnulf Stenzl a, Claus D. Claussen b, Heinz-Peter Schlemmer b
Address for correspondence: Aristotelis G. Anastasiadis, M.D., Department of Urology, Eberhard-Karls-Universität Tuebingen, Hoppe-Seyler-Strasse 3, 72076 Tübingen, Germany.Résumé |
A 65-year-old patient was examined with [11C]-choline positron emission tomography-computed tomography and magnetic resonance imaging (MRI) for possible tumor detection after two negative sessions of transrectal ultrasound-guided prostate biopsy and persistently elevated prostate-specific antigen levels for 27 months. Choline positron emission tomography revealed a small and circumscribed pathologic tracer uptake in the right dorsal peripheral gland. Whereas T2-weighted MRI and high b-value diffusion-weighted imaging were able to reproduce this suspicious area, proton MR spectroscopy showed no significant increase of the amplitude of choline-containing compounds. Magnetic resonance imaging-guided prostate biopsy was successfully performed. All specimens taken from the lesion showed a Gleason 5 tubular adenocarcinoma with low proliferative activity.
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Vol 69 - N° 6
P. 1208.e5-1208.e8 - juin 2007 Retour au numéro
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